A Fixed-Depth Microneedle Enhances Reproducibility and Safety for Corneal Gene Therapy

Drug delivery directly to the corneal stroma currently relies on microscopic injections that demonstrate low reproducibility and clinician-dependent variability. With use of biological drugs such as adeno-associated viral (AAV) vectors, precise and consistent drug deposition is critical to reduce co...

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Detalles Bibliográficos
Autores principales: Gilger, Brian C., Crabtree, Elizabeth, Song, Liujiang, Llanga, Telmo, Cullen, Megan, Blanchard, Allison, Salmon, Jacklyn, Patel, Samirkumar, Zarnitsyn, Vladimir, Hirsch, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornea 2020
Materias:
Basic Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015188/
https://www.ncbi.nlm.nih.gov/pubmed/31724981
http://dx.doi.org/10.1097/ICO.0000000000002182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015188/
https://www.ncbi.nlm.nih.gov/pubmed/31724981
http://dx.doi.org/10.1097/ICO.0000000000002182

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