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Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia

BACKGROUND: The majority of patients with advanced cancer develop cachexia, a weight loss syndrome that severely reduces quality of life and limits survival. Our understanding of the underlying mechanisms that cause the condition is limited, and there are currently no treatment options that can comp...

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Detalles Bibliográficos
Autores principales: Pettersen, Kristine, Andersen, Sonja, van der Veen, Anna, Nonstad, Unni, Hatakeyama, Shinji, Lambert, Christian, Lach‐Trifilieff, Estelle, Moestue, Siver, Kim, Jana, Grønberg, Bjørn Henning, Schilb, Alain, Jacobi, Carsten, Bjørkøy, Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015233/
https://www.ncbi.nlm.nih.gov/pubmed/31436048
http://dx.doi.org/10.1002/jcsm.12489