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Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia
BACKGROUND: The majority of patients with advanced cancer develop cachexia, a weight loss syndrome that severely reduces quality of life and limits survival. Our understanding of the underlying mechanisms that cause the condition is limited, and there are currently no treatment options that can comp...
Autores principales: | Pettersen, Kristine, Andersen, Sonja, van der Veen, Anna, Nonstad, Unni, Hatakeyama, Shinji, Lambert, Christian, Lach‐Trifilieff, Estelle, Moestue, Siver, Kim, Jana, Grønberg, Bjørn Henning, Schilb, Alain, Jacobi, Carsten, Bjørkøy, Geir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015233/ https://www.ncbi.nlm.nih.gov/pubmed/31436048 http://dx.doi.org/10.1002/jcsm.12489 |
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