Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis‐associated cachexia

BACKGROUND: Ctns(−/−) mice, a mouse model of infantile nephropathic cystinosis, exhibit hypermetabolism with adipose tissue browning and profound muscle wasting. Ctns(−/−) mice are 25(OH)D(3) and 1,25(OH)(2)D(3) insufficient. We investigated whether vitamin D repletion could ameliorate adipose tissu...

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Detalles Bibliográficos
Autores principales: Cheung, Wai W., Hao, Sheng, Wang, Zhen, Ding, Wei, Zheng, Ronghao, Gonzalez, Alex, Zhan, Jian‐Ying, Zhou, Ping, Li, Shiping, Esparza, Mary C., Hoffman, Hal M., Lieber, Richard L., Mak, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015252/
https://www.ncbi.nlm.nih.gov/pubmed/31721480
http://dx.doi.org/10.1002/jcsm.12497

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