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A stochastic model for simulating ribosome kinetics in vivo

Computational modelling of in vivo protein synthesis is highly complicated, as it requires the simulation of ribosomal movement over the entire transcriptome, as well as consideration of the concentration effects from 40+ different types of tRNAs and numerous other protein factors. Here I report on...

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Detalles Bibliográficos
Autor principal: Dykeman, Eric Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015319/
https://www.ncbi.nlm.nih.gov/pubmed/32049979
http://dx.doi.org/10.1371/journal.pcbi.1007618