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The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane

Matriptase plays important roles in epithelial integrity and function, which depend on its sorting to the basolateral surface of cells, where matriptase zymogen is converted to an active enzyme in order to act on its substrates. After activation, matriptase undergoes HAI-1-mediated inhibition, inter...

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Detalles Bibliográficos
Autores principales: Tseng, Chun-Che, Jia, Bailing, Barndt, Robert B., Dai, Yang-Hong, Chen, Yu Hsin, Du, Po-Wen A., Wang, Jehng-Kang, Tang, Hung-Jen, Lin, Chen-Yong, Johnson, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015431/
https://www.ncbi.nlm.nih.gov/pubmed/32049977
http://dx.doi.org/10.1371/journal.pone.0228874