Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features

The infection caused by methicillin-resistant Staphylococcus aureus (MRSA) is a global threat to public health. Vancomycin remains one of the first-line drugs for the treatment of MRSA infections. However, S. aureus isolates with complete resistance to vancomycin have emerged in recent years. Vancom...

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Detalles Bibliográficos
Autores principales: Cong, Yanguang, Yang, Sijin, Rao, Xiancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015472/
https://www.ncbi.nlm.nih.gov/pubmed/32071785
http://dx.doi.org/10.1016/j.jare.2019.10.005
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author Cong, Yanguang
Yang, Sijin
Rao, Xiancai
author_facet Cong, Yanguang
Yang, Sijin
Rao, Xiancai
author_sort Cong, Yanguang
collection PubMed
description The infection caused by methicillin-resistant Staphylococcus aureus (MRSA) is a global threat to public health. Vancomycin remains one of the first-line drugs for the treatment of MRSA infections. However, S. aureus isolates with complete resistance to vancomycin have emerged in recent years. Vancomycin-resistant S. aureus (VRSA) is mediated by a vanA gene cluster, which is transferred from vancomycin-resistant enterococcus. Since the first VRSA isolate was recovered from Michigan, USA in 2002, 52 VRSA strains have been isolated worldwide. In this paper, we review the latest progresses in VRSA, highlighting its resistance mechanism, characteristics of VRSA infections, as well as clinical treatments.
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spelling pubmed-70154722020-02-18 Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features Cong, Yanguang Yang, Sijin Rao, Xiancai J Adv Res Review Article The infection caused by methicillin-resistant Staphylococcus aureus (MRSA) is a global threat to public health. Vancomycin remains one of the first-line drugs for the treatment of MRSA infections. However, S. aureus isolates with complete resistance to vancomycin have emerged in recent years. Vancomycin-resistant S. aureus (VRSA) is mediated by a vanA gene cluster, which is transferred from vancomycin-resistant enterococcus. Since the first VRSA isolate was recovered from Michigan, USA in 2002, 52 VRSA strains have been isolated worldwide. In this paper, we review the latest progresses in VRSA, highlighting its resistance mechanism, characteristics of VRSA infections, as well as clinical treatments. Elsevier 2019-10-12 /pmc/articles/PMC7015472/ /pubmed/32071785 http://dx.doi.org/10.1016/j.jare.2019.10.005 Text en © 2019 The Authors. Published by Elsevier B.V. on behalf of Cairo University. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Cong, Yanguang
Yang, Sijin
Rao, Xiancai
Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features
title Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features
title_full Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features
title_fullStr Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features
title_full_unstemmed Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features
title_short Vancomycin resistant Staphylococcus aureus infections: A review of case updating and clinical features
title_sort vancomycin resistant staphylococcus aureus infections: a review of case updating and clinical features
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015472/
https://www.ncbi.nlm.nih.gov/pubmed/32071785
http://dx.doi.org/10.1016/j.jare.2019.10.005
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AT raoxiancai vancomycinresistantstaphylococcusaureusinfectionsareviewofcaseupdatingandclinicalfeatures

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