Cargando…
Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space
Neurons in developing sensory pathways exhibit spontaneous bursts of electrical activity that are critical for survival, maturation and circuit refinement. In the auditory system, intrinsically generated activity arises within the cochlea, but the molecular mechanisms that initiate this activity rem...
Autores principales: | Babola, Travis A, Kersbergen, Calvin J, Wang, Han Chin, Bergles, Dwight E |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015667/ https://www.ncbi.nlm.nih.gov/pubmed/31913121 http://dx.doi.org/10.7554/eLife.52160 |
Ejemplares similares
-
Developmental spontaneous activity promotes formation of sensory domains, frequency tuning and proper gain in central auditory circuits
por: Kersbergen, Calvin J., et al.
Publicado: (2022) -
Preservation of developmental spontaneous activity enables early auditory system maturation in deaf mice
por: Kersbergen, Calvin J., et al.
Publicado: (2023) -
Dual expression of Atoh1 and Ikzf2 promotes transformation of adult cochlear supporting cells into outer hair cells
por: Sun, Suhong, et al.
Publicado: (2021) -
The Kinocilia of Cochlear Hair Cells: Structures, Functions, and Diseases
por: Wang, Difei, et al.
Publicado: (2021) -
Dimensions of a Living Cochlear Hair Bundle
por: Miller, Katharine K., et al.
Publicado: (2021)