Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking

Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and many human disorders, including pathological tissue fibrosis in major organs. How premature collagen proteins in the endoplasmic reticulum (ER) assemble and route for secretion remains molecularly undefined....

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Bai, Meirong, Barbosa, Guilherme Oliveira, Chen, Andrew, Wei, Yuehua, Luo, Shuo, Wang, Xin, Wang, Bingying, Tsukui, Tatsuya, Li, Hao, Sheppard, Dean, Kornberg, Thomas B., Ma, Dengke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015688/
https://www.ncbi.nlm.nih.gov/pubmed/32095531
http://dx.doi.org/10.1126/sciadv.aay7667

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