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Endocannabinoid genetic variation enhances vulnerability to THC reward in adolescent female mice

Adolescence represents a developmental period with the highest risk for initiating cannabis use. Little is known about whether genetic variation in the endocannabinoid system alters mesolimbic reward circuitry to produce vulnerability to the rewarding properties of the exogenous cannabinoid Δ(9)-tet...

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Detalles Bibliográficos
Autores principales: Burgdorf, Caitlin E., Jing, Deqiang, Yang, Ruirong, Huang, Chienchun, Hill, Matthew N., Mackie, Ken, Milner, Teresa A., Pickel, Virginia M., Lee, Francis S., Rajadhyaksha, Anjali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015690/
https://www.ncbi.nlm.nih.gov/pubmed/32095523
http://dx.doi.org/10.1126/sciadv.aay1502