Comparison of pharmacokinetics, safety and tolerability of secukinumab administered subcutaneously using different delivery systems in healthy volunteers and in psoriasis patients

AIMS: The aim of the study was to compare the pharmacokinetics (PK), safety and tolerability of secukinumab with different devices for subcutaneous (s.c.) administration of 2 mL. METHODS: A phase 1 study in healthy subjects with 6 devices to administer 2 mL injection volumes was conducted to evaluat...

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Detalles Bibliográficos
Autores principales: Bruin, Gerard, Hockey, Hans‐Ulrich P., La Stella, Phillip, Sigurgeirsson, Bárdur, Fu, Rong, Patekar, Manmath, Charef, Pascal, Woessner, Ralph, Boutouyrie‐Dumont, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015744/
https://www.ncbi.nlm.nih.gov/pubmed/31658377
http://dx.doi.org/10.1111/bcp.14155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015744/
https://www.ncbi.nlm.nih.gov/pubmed/31658377
http://dx.doi.org/10.1111/bcp.14155

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