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Population pharmacokinetics of vancomycin in obesity: Finding the optimal dose for (morbidly) obese individuals
AIMS: For vancomycin treatment in obese patients, there is no consensus on the optimal dose that will lead to the pharmacodynamic target (area under the curve 400–700 mg h L(−1)). This prospective study quantifies vancomycin pharmacokinetics in morbidly obese and nonobese individuals, in order to gu...
Autores principales: | Smit, Cornelis, Wasmann, Roeland E., Goulooze, Sebastiaan C., Wiezer, Marinus J., van Dongen, Eric P.A., Mouton, Johan W., Brüggemann, Roger J.M., Knibbe, Catherijne A.J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015748/ https://www.ncbi.nlm.nih.gov/pubmed/31661553 http://dx.doi.org/10.1111/bcp.14144 |
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