Prevention of tuberculosis in macaques after intravenous BCG immunization

Mycobacterium tuberculosis (Mtb) is the leading cause of death from infection worldwide(1). The only available vaccine, BCG (Bacillus Calmette–Guérin), is given intradermally and has variable efficacy against pulmonary tuberculosis, the major cause of mortality and disease transmission(1,2). Here we...

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Detalles Bibliográficos
Autores principales: Darrah, Patricia A., Zeppa, Joseph J., Maiello, Pauline, Hackney, Joshua A., Wadsworth, Marc H., Hughes, Travis K., Pokkali, Supriya, Swanson, Phillip A., Grant, Nicole L., Rodgers, Mark A., Kamath, Megha, Causgrove, Chelsea M., Laddy, Dominick J., Bonavia, Aurelio, Casimiro, Danilo, Lin, Philana Ling, Klein, Edwin, White, Alexander G., Scanga, Charles A., Shalek, Alex K., Roederer, Mario, Flynn, JoAnne L., Seder, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015856/
https://www.ncbi.nlm.nih.gov/pubmed/31894150
http://dx.doi.org/10.1038/s41586-019-1817-8

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