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The molecular chaperone β-casein prevents amorphous and fibrillar aggregation of α-lactalbumin by stabilisation of dynamic disorder

Deficits in protein homeostasis (proteostasis) are typified by the partial unfolding or misfolding of native proteins leading to amorphous or fibrillar aggregation, events that have been closely associated with diseases including Alzheimer's and Parkinson's diseases. Molecular chaperones a...

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Detalles Bibliográficos
Autores principales: Sanders, Henry M., Jovcevski, Blagojce, Carver, John A., Pukala, Tara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015860/
https://www.ncbi.nlm.nih.gov/pubmed/31939601
http://dx.doi.org/10.1042/BCJ20190638

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