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Plinabulin ameliorates neutropenia induced by multiple chemotherapies through a mechanism distinct from G-CSF therapies

PURPOSE: Chemotherapy-induced neutropenia (CIN) increases the risk of infections and mortality in cancer patients. G-CSF therapies are approved for the treatment of CIN, but non-G-CSF therapies are needed to increase efficacy and minimize side effects. Plinabulin is an inhibitor of tubulin polymeriz...

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Detalles Bibliográficos
Autores principales:	Tonra, James R., Lloyd, G. Kenneth, Mohanlal, Ramon, Huang, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015961/ https://www.ncbi.nlm.nih.gov/pubmed/31811421 http://dx.doi.org/10.1007/s00280-019-03998-w

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