Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report

Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness (DOC) that hinders their rehabilitative process, and is strongly correlated with pain reducing patients’ quality of life. In these patients, abnormal postures may occur as an expression of se...

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Autores principales: Pingue, Valeria, Gentili, Marta, Losurdo, Anna, Clementi, Emilio, Nardone, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015971/
https://www.ncbi.nlm.nih.gov/pubmed/32116516
http://dx.doi.org/10.3389/fnins.2020.00070
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author Pingue, Valeria
Gentili, Marta
Losurdo, Anna
Clementi, Emilio
Nardone, Antonio
author_facet Pingue, Valeria
Gentili, Marta
Losurdo, Anna
Clementi, Emilio
Nardone, Antonio
author_sort Pingue, Valeria
collection PubMed
description Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness (DOC) that hinders their rehabilitative process, and is strongly correlated with pain reducing patients’ quality of life. In these patients, abnormal postures may occur as an expression of severe brain damage. Here we present the case of a 52-year-old man in decorticate rigidity following a hypoxic–ischemic encephalopathy due to myocardial infarction who showed improvement of spasticity of upper limbs following intake of levetiracetam combined with the conventional neurorehabilitation program.
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spelling pubmed-70159712020-02-28 Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report Pingue, Valeria Gentili, Marta Losurdo, Anna Clementi, Emilio Nardone, Antonio Front Neurosci Neuroscience Severe spasticity is a frequent and disabling complication in patients presenting disorders of consciousness (DOC) that hinders their rehabilitative process, and is strongly correlated with pain reducing patients’ quality of life. In these patients, abnormal postures may occur as an expression of severe brain damage. Here we present the case of a 52-year-old man in decorticate rigidity following a hypoxic–ischemic encephalopathy due to myocardial infarction who showed improvement of spasticity of upper limbs following intake of levetiracetam combined with the conventional neurorehabilitation program. Frontiers Media S.A. 2020-02-06 /pmc/articles/PMC7015971/ /pubmed/32116516 http://dx.doi.org/10.3389/fnins.2020.00070 Text en Copyright © 2020 Pingue, Gentili, Losurdo, Clementi and Nardone. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Pingue, Valeria
Gentili, Marta
Losurdo, Anna
Clementi, Emilio
Nardone, Antonio
Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report
title Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report
title_full Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report
title_fullStr Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report
title_full_unstemmed Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report
title_short Levetiracetam Improves Upper Limb Spasticity in a Patient With Unresponsive Wakefulness Syndrome: A Case Report
title_sort levetiracetam improves upper limb spasticity in a patient with unresponsive wakefulness syndrome: a case report
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015971/
https://www.ncbi.nlm.nih.gov/pubmed/32116516
http://dx.doi.org/10.3389/fnins.2020.00070
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