Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics

In order to rapidly identify the phenotypic profile and possible off-target liability effects of novel synthesized thyromimetics for selection of lead compounds for further optimization studies, we performed in vitro screening on a new small library of synthetic thyromimetics. A comprehensive panel...

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Detalles Bibliográficos
Autores principales: Runfola, Massimiliano, Sestito, Simona, Gul, Sheraz, Chiellini, Grazia, Rapposelli, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015999/
https://www.ncbi.nlm.nih.gov/pubmed/32071982
http://dx.doi.org/10.1016/j.dib.2020.105206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015999/
https://www.ncbi.nlm.nih.gov/pubmed/32071982
http://dx.doi.org/10.1016/j.dib.2020.105206

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