Targeting Src family kinase member Fyn by Saracatinib attenuated liver fibrosis in vitro and in vivo

Recent studies suggest that Src family kinase (SFK) plays important roles in systemic sclerosis and pulmonary fibrosis. However, how SFKs contributed to the pathogenesis of liver fibrosis remains largely unknown. Here, we investigated the role of Fyn, a member of SFK, in hepatic stellate cell (HSC)...

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Detalles Bibliográficos
Autores principales: Du, Guifang, Wang, Jing, Zhang, Ting, Ding, Qiang, Jia, Xiaodong, Zhao, Xueke, Dong, Jinke, Yang, Xinrui, Lu, Shanshan, Zhang, Cuihong, Liu, Ze, Zeng, Zhen, Safadi, Rifaat, Qi, Ruizhao, Zhao, Xin, Hong, Zhixian, Lu, Yinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016006/
https://www.ncbi.nlm.nih.gov/pubmed/32051399
http://dx.doi.org/10.1038/s41419-020-2229-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016006/
https://www.ncbi.nlm.nih.gov/pubmed/32051399
http://dx.doi.org/10.1038/s41419-020-2229-2

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