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The importance of definitions in the study of polyQ regions: A tale of thresholds, impurities and sequence context
Polyglutamine (polyQ) regions are one of the most prevalent homorepeats in eukaryotes. It is however difficult to evaluate their prevalence because various studies claim different results. The reason is the lack of a consensus to define what is indeed a polyQ region. We have tackled this issue by st...
Autores principales: | Mier, Pablo, Elena-Real, Carlos, Urbanek, Annika, Bernadó, Pau, Andrade-Navarro, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016039/ https://www.ncbi.nlm.nih.gov/pubmed/32071707 http://dx.doi.org/10.1016/j.csbj.2020.01.012 |
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