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Characterization of HIV-1 diversity in various compartments at the time of primary infection by ultradeep sequencing

We used next-generation sequencing to evaluate the quantity and genetic diversity of the HIV envelope gene in various compartments in eight patients with acute infection. Plasma (PL) and seminal fluid (SF) were available for all patients, whole blood (WB) for seven, non-spermatozoid cells (NSC) for...

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Detalles Bibliográficos
Autores principales: Gaube, Géraldine, Armero, Alix, Salmona, Maud, Néré, Marie-Laure, Mahjoub, Nadia, Lascoux-Combe, Caroline, Gabassi, Audrey, Gallien, Sébastien, Amara, Ali, Molina, Jean Michel, Delaugerre, Constance, Chaix, Marie-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016127/
https://www.ncbi.nlm.nih.gov/pubmed/32051463
http://dx.doi.org/10.1038/s41598-020-59234-6