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Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018

Vaccinating dogs against rabies is an effective means of reducing human rabies. We subjected 1327 clinically diagnosed human rabies death and mass dog vaccination (MDV) data during 2006–2018 to quantify the impacts of MDV on human rabies incidence in Bangladesh and a subset of rabies death data (422...

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Autores principales: Ghosh, Sumon, Rana, Md. Sohel, Islam, Md. Kamrul, Chowdhury, Sukanta, Haider, Najmul, Kafi, Mohammad Abdullah Heel, Ullah, Sayed Mohammed, Shah, Md. Rashed Ali, Jahan, Afsana Akter, Mursalin, Hasan Sayedul, Marma, Aung Swi Prue, Ali, S. M. Emran, Hossain, Shohrab, Bhowmik, Rajub, Debnath, Nitish C., Shamsuzzaman, Abul Khair Mohammad, Ahmed, Be-Nazir, Siddiqi, Umme Ruman, Jhora, Sanya Tahmina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016137/
https://www.ncbi.nlm.nih.gov/pubmed/32051481
http://dx.doi.org/10.1038/s41598-020-59109-w
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author Ghosh, Sumon
Rana, Md. Sohel
Islam, Md. Kamrul
Chowdhury, Sukanta
Haider, Najmul
Kafi, Mohammad Abdullah Heel
Ullah, Sayed Mohammed
Shah, Md. Rashed Ali
Jahan, Afsana Akter
Mursalin, Hasan Sayedul
Marma, Aung Swi Prue
Ali, S. M. Emran
Hossain, Shohrab
Bhowmik, Rajub
Debnath, Nitish C.
Shamsuzzaman, Abul Khair Mohammad
Ahmed, Be-Nazir
Siddiqi, Umme Ruman
Jhora, Sanya Tahmina
author_facet Ghosh, Sumon
Rana, Md. Sohel
Islam, Md. Kamrul
Chowdhury, Sukanta
Haider, Najmul
Kafi, Mohammad Abdullah Heel
Ullah, Sayed Mohammed
Shah, Md. Rashed Ali
Jahan, Afsana Akter
Mursalin, Hasan Sayedul
Marma, Aung Swi Prue
Ali, S. M. Emran
Hossain, Shohrab
Bhowmik, Rajub
Debnath, Nitish C.
Shamsuzzaman, Abul Khair Mohammad
Ahmed, Be-Nazir
Siddiqi, Umme Ruman
Jhora, Sanya Tahmina
author_sort Ghosh, Sumon
collection PubMed
description Vaccinating dogs against rabies is an effective means of reducing human rabies. We subjected 1327 clinically diagnosed human rabies death and mass dog vaccination (MDV) data during 2006–2018 to quantify the impacts of MDV on human rabies incidence in Bangladesh and a subset of rabies death data (422) for clinico-epidemiological analysis. A positive and increasing trend of MDV (p = 0.01 and tau = 0.71) and a negative and declining trend (p < 0.001 and tau = −0.88) of human rabies cases (Correlation coefficient: −0.82) have been observed. Among 422 deaths, the majority (78%) of the victims sought treatment from traditional healers, and 12% received post-exposure prophylaxis (PEP). The mean incubation period of rabies in cases with exposure sites on the head & neck (35 days) was shorter than the upper limb (mean = 64 days, p = 0.02) and lower limb (mean = 89 days, p < 0.01). MDV has been found to be effective for reducing human rabies cases in Bangladesh. Creating awareness among the animal bite victims to stop reliance on traditional healers rather seeking PEP, addressing the role of traditional healers through awareness education programme with respect to the treatment of dog bites, ensuring availability of PEP, and continuing to scale up MDV may help to prevent human rabies deaths.
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spelling pubmed-70161372020-02-21 Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018 Ghosh, Sumon Rana, Md. Sohel Islam, Md. Kamrul Chowdhury, Sukanta Haider, Najmul Kafi, Mohammad Abdullah Heel Ullah, Sayed Mohammed Shah, Md. Rashed Ali Jahan, Afsana Akter Mursalin, Hasan Sayedul Marma, Aung Swi Prue Ali, S. M. Emran Hossain, Shohrab Bhowmik, Rajub Debnath, Nitish C. Shamsuzzaman, Abul Khair Mohammad Ahmed, Be-Nazir Siddiqi, Umme Ruman Jhora, Sanya Tahmina Sci Rep Article Vaccinating dogs against rabies is an effective means of reducing human rabies. We subjected 1327 clinically diagnosed human rabies death and mass dog vaccination (MDV) data during 2006–2018 to quantify the impacts of MDV on human rabies incidence in Bangladesh and a subset of rabies death data (422) for clinico-epidemiological analysis. A positive and increasing trend of MDV (p = 0.01 and tau = 0.71) and a negative and declining trend (p < 0.001 and tau = −0.88) of human rabies cases (Correlation coefficient: −0.82) have been observed. Among 422 deaths, the majority (78%) of the victims sought treatment from traditional healers, and 12% received post-exposure prophylaxis (PEP). The mean incubation period of rabies in cases with exposure sites on the head & neck (35 days) was shorter than the upper limb (mean = 64 days, p = 0.02) and lower limb (mean = 89 days, p < 0.01). MDV has been found to be effective for reducing human rabies cases in Bangladesh. Creating awareness among the animal bite victims to stop reliance on traditional healers rather seeking PEP, addressing the role of traditional healers through awareness education programme with respect to the treatment of dog bites, ensuring availability of PEP, and continuing to scale up MDV may help to prevent human rabies deaths. Nature Publishing Group UK 2020-02-12 /pmc/articles/PMC7016137/ /pubmed/32051481 http://dx.doi.org/10.1038/s41598-020-59109-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Ghosh, Sumon
Rana, Md. Sohel
Islam, Md. Kamrul
Chowdhury, Sukanta
Haider, Najmul
Kafi, Mohammad Abdullah Heel
Ullah, Sayed Mohammed
Shah, Md. Rashed Ali
Jahan, Afsana Akter
Mursalin, Hasan Sayedul
Marma, Aung Swi Prue
Ali, S. M. Emran
Hossain, Shohrab
Bhowmik, Rajub
Debnath, Nitish C.
Shamsuzzaman, Abul Khair Mohammad
Ahmed, Be-Nazir
Siddiqi, Umme Ruman
Jhora, Sanya Tahmina
Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018
title Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018
title_full Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018
title_fullStr Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018
title_full_unstemmed Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018
title_short Trends and clinico-epidemiological features of human rabies cases in Bangladesh 2006–2018
title_sort trends and clinico-epidemiological features of human rabies cases in bangladesh 2006–2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016137/
https://www.ncbi.nlm.nih.gov/pubmed/32051481
http://dx.doi.org/10.1038/s41598-020-59109-w
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