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Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness
Antibody-mediated immune responses rely on antigen recognition by the B cell antigen receptor (BCR) and the proper engagement of its intracellular signal effector proteins. Src homology (SH) 2 domain-containing leukocyte protein of 65 kDa (SLP65) is the key scaffold protein mediating BCR signaling....
Autores principales: | Wong, Leo E., Bhatt, Arshiya, Erdmann, Philipp S., Hou, Zhen, Maier, Joachim, Pirkuliyeva, Sona, Engelke, Michael, Becker, Stefan, Plitzko, Jürgen, Wienands, Jürgen, Griesinger, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016142/ https://www.ncbi.nlm.nih.gov/pubmed/32051419 http://dx.doi.org/10.1038/s41467-020-14544-1 |
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