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Strong Immune Responses Induced by Direct Local Injections of Modified mRNA-Lipid Nanocomplexes
In vitro transcribed mRNAs hold the promises of many medical applications in disease prevention and treatment, such as replacement or supplement of missing or inadequately expressed endogenous proteins and as preventive vaccines against infectious diseases, therapeutic vaccines, or other protein-bas...
Autores principales: | Arya, Smriti, Lin, Qiubin, Zhou, Nan, Gao, Xiang, Huang, Jian-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016160/ https://www.ncbi.nlm.nih.gov/pubmed/32059336 http://dx.doi.org/10.1016/j.omtn.2019.12.044 |
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