Degradation of proteins by PROTACs and other strategies

Blocking the biological functions of scaffold proteins and aggregated proteins is a challenging goal. PROTAC proteolysis-targeting chimaera (PROTAC) technology may be the solution, considering its ability to selectively degrade target proteins. Recent progress in the PROTAC strategy include identifi...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Jiang, Xueyang, Feng, Feng, Liu, Wenyuan, Sun, Haopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016280/
https://www.ncbi.nlm.nih.gov/pubmed/32082969
http://dx.doi.org/10.1016/j.apsb.2019.08.001

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