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Peptides of major basic protein and eosinophil cationic protein activate human mast cells

The eosinophil granule proteins, major basic protein (MBP) and eosinophil cationic protein (ECP), activate mast cells during inflammation; however the mechanism responsible for this activity is poorly understood. We found that some theoretical tryptase-digested fragments of MBP and ECP induced degra...

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Detalles Bibliográficos
Autores principales: Ogasawara, Hiroyuki, Furuno, Masahiro, Edamura, Koji, Noguchi, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016281/
https://www.ncbi.nlm.nih.gov/pubmed/32072023
http://dx.doi.org/10.1016/j.bbrep.2019.100719