PCC0208017, a novel small-molecule inhibitor of MARK3/MARK4, suppresses glioma progression in vitro and in vivo

Gliomas are the most common primary intracranial neoplasms among all brain malignancies, and the microtubule affinity regulating kinases (MARKs) have become potential drug targets for glioma. Here, we report a novel dual small-molecule inhibitor of MARK3 and MARK4, designated as PCC0208017. In vitro...

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Detalles Bibliográficos
Autores principales: Li, Fangfang, Liu, Zongliang, Sun, Heyuan, Li, Chunmei, Wang, Wenyan, Ye, Liang, Yan, Chunhong, Tian, Jingwei, Wang, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016295/
https://www.ncbi.nlm.nih.gov/pubmed/32082974
http://dx.doi.org/10.1016/j.apsb.2019.09.004

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