Lineage reprogramming of fibroblasts into induced cardiac progenitor cells by CRISPR/Cas9-based transcriptional activators

Overexpression of exogenous lineage-determining factors succeeds in directly reprogramming fibroblasts to various cell types. Several studies have reported reprogramming of fibroblasts into induced cardiac progenitor cells (iCPCs). CRISPR/Cas9-mediated gene activation is a potential approach for cel...

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Detalles Bibliográficos
Autores principales: Wang, Jianglin, Jiang, Xueyan, Zhao, Lixin, Zuo, Shengjia, Chen, Xiantong, Zhang, Lingmin, Lin, Zhongxiao, Zhao, Xiaoya, Qin, Yuyan, Zhou, Xinke, Yu, Xi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016296/
https://www.ncbi.nlm.nih.gov/pubmed/32082976
http://dx.doi.org/10.1016/j.apsb.2019.09.003

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