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Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines
Tissue-resident macrophages play critical roles in controlling homeostasis, tissue repair, and immunity. Inflammatory macrophages can sustain tissue damage and promote the development of fibrosis during infections and sterile tissue injury. The NLRP3 inflammasome and its effector cytokine IL-1β have...
Autores principales: | Köse-Vogel, Nilay, Stengel, Sven, Gardey, Elena, Kirchberger-Tolstik, Tatiana, Reuken, Philipp A., Stallmach, Andreas, Bruns, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016608/ https://www.ncbi.nlm.nih.gov/pubmed/31905600 http://dx.doi.org/10.3390/cells9010079 |
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