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Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing

The preservation of genome integrity in the mammalian female germline from primordial follicle arrest to activation of growth to oocyte maturation is fundamental to ensure reproductive success. As oocytes are formed before birth and may remain dormant for many years, it is essential that defence mec...

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Detalles Bibliográficos
Autores principales:	Maidarti, Mila, Anderson, Richard A., Telfer, Evelyn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016612/ https://www.ncbi.nlm.nih.gov/pubmed/31947601 http://dx.doi.org/10.3390/cells9010200

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