Cargando…

IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway

The Insulin-like Growth Factor I (IGF-1) signalling pathway is essential for cell growth and facilitates tumourogenic processes. We recently reported that IGF-1 induces a transcriptional programme for mitochondrial biogenesis, while also inducing expression of the mitophagy receptor BCL2/adenovirus...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riis, Sarah, Murray, Joss B., O’Connor, Rosemary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016769/ https://www.ncbi.nlm.nih.gov/pubmed/31936236 http://dx.doi.org/10.3390/cells9010147

Ejemplares similares

Bnip3 as a Dual Regulator of Mitochondrial Turnover and Cell Death in the Myocardium
por: Gustafsson, Åsa B.
Publicado: (2011)

GSK-3 and mitochondria in cancer cells
por: Chiara, Federica, et al.
Publicado: (2013)

BNIP3 and NIX Mediate Mieap-Induced Accumulation of Lysosomal Proteins within Mitochondria
por: Nakamura, Yasuyuki, et al.
Publicado: (2012)

Lipid droplet turnover at the lysosome inhibits growth of hepatocellular carcinoma in a BNIP3-dependent manner
por: Berardi, Damian E., et al.
Publicado: (2022)

The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy
por: Gok, Mehmet Oguz, et al.
Publicado: (2023)

Curcumin prevents As(3+)-induced carcinogenesis through regulation of GSK3β/Nrf2
por: Dang, Yuan-Ye, et al.
Publicado: (2021)

DNA methylation of the promoter region of bnip3 and bnip3l genes induced by metabolic programming
por: Veron, Vincent, et al.
Publicado: (2018)

GSK3β Is Involved in the Relief of Mitochondria Pausing in a Tau-Dependent Manner
por: Llorens-Martín, María, et al.
Publicado: (2011)

Inhibition of BMK1 pathway suppresses cancer stem cells through BNIP3 and BNIP3L
por: Song, Chengli, et al.
Publicado: (2015)

The Role of Insulin/IGF-1/PI3K/Akt/GSK3β Signaling in Parkinson's Disease Dementia
por: Yang, Liying, et al.
Publicado: (2018)

The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy
por: Delgado, Jose M, et al.
Publicado: (2023)

IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer
por: Glaß, Markus, et al.
Publicado: (2021)

BNIP3 in Lung Cancer: To Kill or Rescue?
por: Gorbunova, Anna S., et al.
Publicado: (2020)

Novel Reporter Alleles of GSK-3α and GSK-3β
por: Barrell, William B., et al.
Publicado: (2012)

Aberrant regulation of the GSK‐3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy
por: Ranea‐Robles, Pablo, et al.
Publicado: (2018)

Selective GSK3β Inhibition Mediates an Nrf2-Independent Anti-inflammatory Microglial Response
por: Yousef, Mohamed H., et al.
Publicado: (2022)

Different expression of GSK3β and pS9GSK3β depending on phenotype of cervical cancer: possible association of GSK3β with squamous cell carcinoma and pS9GSK3β with adenocarcinoma
por: Ahn, Kwanghee, et al.
Publicado: (2019)

Proteomic Identification of 14-3-3ζ as an Adapter for IGF-1 and Akt/GSK-3β Signaling and Survival of Renal Mesangial Cells
por: Singh, Lalit P., et al.
Publicado: (2006)

TAp73 transcriptionally represses BNIP3 expression
por: Petrova, Varvara, et al.
Publicado: (2015)

BNIP3 expression in bovine follicle and corpus luteum
por: NISHIMURA, Ryo, et al.
Publicado: (2017)

The histone H3K9 demethylase KDM3A promotes anoikis by transcriptionally activating pro-apoptotic genes BNIP3 and BNIP3L
por: Pedanou, Victoria E, et al.
Publicado: (2016)

GSK-3β, a double-edged sword in Nrf2 regulation: Implications for neurological dysfunction and disease
por: Culbreth, Megan, et al.
Publicado: (2018)

Shikonin Attenuates Acetaminophen-Induced Hepatotoxicity by Upregulation of Nrf2 through Akt/GSK3β Signaling
por: Li, Huachao, et al.
Publicado: (2018)

Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling
por: Duan, Jialin, et al.
Publicado: (2019)

Regulation of Endoplasmic Reticulum–Mitochondria Tethering and Ca(2+) Fluxes by TDP-43 via GSK3β
por: Peggion, Caterina, et al.
Publicado: (2021)

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β
por: Cymerman, Iwona A., et al.
Publicado: (2015)

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
por: Gozdz, Agata, et al.
Publicado: (2017)

GSK-3β and memory formation
por: Takashima, Akihiko
Publicado: (2012)

GSK3β and aging liver
por: Jin, Jingling, et al.
Publicado: (2009)

GSK3β and the aging kidney
por: Kreidberg, Jordan A., et al.
Publicado: (2022)

The Role of GSK-3β in the Regulation of Protein Turnover, Myosin Phenotype, and Oxidative Capacity in Skeletal Muscle under Disuse Conditions
por: Mirzoev, Timur M., et al.
Publicado: (2021)

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis
por: Castillo-Quan, Jorge Iván, et al.
Publicado: (2016)

BNIP3L/NIX regulates both mitophagy and pexophagy
por: Wilhelm, Léa P, et al.
Publicado: (2022)

Opposing Roles of GSK3α and GSK3β Phosphorylation in Platelet Function and Thrombosis
por: Moore, Samantha F., et al.
Publicado: (2021)

GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion
por: Chen, Xi, et al.
Publicado: (2016)

Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway
por: Lv, Hongming, et al.
Publicado: (2019)

Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation
por: Das, Rashmi, et al.
Publicado: (2020)

GSK3β-SCF(FBXW7α) mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover
por: Garvin, Alexander J, et al.
Publicado: (2019)

GSK3β loosens the CLASP on microtubules
por: Short, Ben
Publicado: (2009)

AKT/GSK3β Signaling in Glioblastoma
por: Majewska, Ewelina, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_oj622sk98p5kihfm2a9m20ntg0