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Differential Depletion of Bone Marrow Resident B-ALL after Systemic Administration of Endosomal TLR Agonists

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. While frontline chemotherapy regimens are generally very effective, the prognosis for patients whose leukemia returns remains poor. The presence of measurable residual disease (MRD) in bone marrow at the completion of induct...

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Detalles Bibliográficos
Autores principales: Jo, Sumin, Fotovati, Abbas, Duque-Afonso, Jesus, Cleary, Michael L., van den Elzen, Peter, Seif, Alix E., Reid, Gregor S.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016792/
https://www.ncbi.nlm.nih.gov/pubmed/32015298
http://dx.doi.org/10.3390/cancers12010169