Cargando…

Small RNA Profiling of piRNAs in Colorectal Cancer Identifies Consistent Overexpression of piR-24000 That Correlates Clinically with an Aggressive Disease Phenotype

Piwi-interacting RNAs (piRNAs) represent a novel class of small non-coding RNAs (ncRNAs) that have been shown to have a deregulated expression in several cancers, although their clinical significance in colorectal cancer (CRC) remains unclear. With an aim of delineating the piRNA distribution in CRC...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iyer, Deepak Narayanan, Wan, Timothy Ming-Hun, Man, Johnny Hon-Wai, Sin, Ryan Wai-Yan, Li, Xue, Lo, Oswens Siu-Hung, Foo, Dominic Chi-Chung, Pang, Roberta Wen-Chi, Law, Wai-Lun, Ng, Lui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016796/ https://www.ncbi.nlm.nih.gov/pubmed/31940941 http://dx.doi.org/10.3390/cancers12010188

Ejemplares similares

Editorial: Evolving roles of piRNAs in solid tumors
por: Ng, Lui, et al.
Publicado: (2023)

A Pilot Study Investigating the Expression Levels of Pluripotency-Associated Genes in Rectal Swab Samples for Colorectal Polyp and Cancer Diagnosis and Prognosis
por: Sin, Ryan Wai-Yan, et al.
Publicado: (2021)

MiR-509-3p is oncogenic, targets the tumor suppressor PHLPP2, and functions as a novel tumor adjacent normal tissue based prognostic biomarker in colorectal cancer
por: Iyer, Deepak Narayanan, et al.
Publicado: (2022)

High Levels of Tumor miR-187-3p—A Potential Tumor-Suppressor microRNA—Are Correlated with Poor Prognosis in Colorectal Cancer
por: Ng, Lui, et al.
Publicado: (2022)

pirScan: a webserver to predict piRNA targeting sites and to avoid transgene silencing in C. elegans
por: Wu, Wei-Sheng, et al.
Publicado: (2018)

Serum microRNA Levels as a Biomarker for Diagnosing Non-Alcoholic Fatty Liver Disease in Chinese Colorectal Polyp Patients
por: Ng, Lui, et al.
Publicado: (2023)

Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center
por: Chan, Toi Yin, et al.
Publicado: (2019)

Identification of serum miR-139-3p as a non-invasive biomarker for colorectal cancer
por: Ng, Lui, et al.
Publicado: (2017)

Rare complication of inflammatory bowel disease-like colitis from glycogen storage disease type 1b and its surgical management: A case report
por: Lui, Frederick Chi-Wai, et al.
Publicado: (2021)

Ribosomes guide pachytene piRNA formation on long intergenic piRNA precursors
por: Sun, Yu H., et al.
Publicado: (2020)

Repurposing DPP-4 Inhibitors for Colorectal Cancer: A Retrospective and Single Center Study
por: Ng, Lui, et al.
Publicado: (2021)

To be or not to be a piRNA: genomic origin and processing of piRNAs
por: Le Thomas, Adrien, et al.
Publicado: (2014)

Identification of piRNAs and piRNA clusters in the testes of the Mongolian horse
por: Li, Bei, et al.
Publicado: (2019)

Cbp80 is needed for the expression of piRNA components and piRNAs
por: Rashpa, Ravish, et al.
Publicado: (2017)

Circulating SNORD57 rather than piR-54265 is a promising biomarker for colorectal cancer: common pitfalls in the study of somatic piRNAs in cancer
por: Tosar, Juan Pablo, et al.
Publicado: (2021)

Sensitized piRNA reporter identifies multiple RNA processing factors involved in piRNA-mediated gene silencing
por: Brown, Jordan, et al.
Publicado: (2023)

PIWI-interacting RNAs piR-13643 and piR-21238 are promising diagnostic biomarkers of papillary thyroid carcinoma
por: Chang, Zhengyan, et al.
Publicado: (2020)

Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
por: Le Thomas, Adrien, et al.
Publicado: (2014)

Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer
por: Lam, Colin Siu-Chi, et al.
Publicado: (2017)

The birth of piRNAs: how mammalian piRNAs are produced, originated, and evolved
por: Sun, Yu H., et al.
Publicado: (2021)

Distinct features of the piRNA pathway in somatic and germ cells: from piRNA cluster transcription to piRNA processing and amplification
por: Théron, Emmanuelle, et al.
Publicado: (2014)

CD26 Induces Colorectal Cancer Angiogenesis and Metastasis through CAV1/MMP1 Signaling
por: Ng, Lui, et al.
Publicado: (2022)

A k-mer scheme to predict piRNAs and characterize locust piRNAs
por: Zhang, Yi, et al.
Publicado: (2011)

piRNA cluster database: a web resource for piRNA producing loci
por: Rosenkranz, David
Publicado: (2016)

High Expression of a Cancer Stemness-Related Gene, Chromobox 8 (CBX8), in Normal Tissue Adjacent to the Tumor (NAT) Is Associated with Poor Prognosis of Colorectal Cancer Patients
por: Ng, Lui, et al.
Publicado: (2022)

The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline
por: Pane, Attilio, et al.
Publicado: (2011)

Diversity of the piRNA pathway for nonself silencing: worm-specific piRNA biogenesis factors
por: Izumi, Natsuko, et al.
Publicado: (2014)

The Expression Dynamics of piRNAs Derived From Male Germline piRNA Clusters and Retrotransposons
por: Kawase, Masaki, et al.
Publicado: (2022)

LSTM4piRNA: Efficient piRNA Detection in Large-Scale Genome Databases Using a Deep Learning-Based LSTM Network
por: Chen, Chun-Chi, et al.
Publicado: (2023)

The Clinicopathological Significance of miR-133a in Colorectal Cancer
por: Wan, Timothy Ming-Hun, et al.
Publicado: (2014)

Profiles of piRNA abundances at emerging or established piRNA loci are determined by local DNA sequences
por: de Vanssay, Augustin, et al.
Publicado: (2013)

TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice
por: Ding, Deqiang, et al.
Publicado: (2018)

Yb body assembly on the flamenco piRNA precursor transcripts reduces genic piRNA production
por: Sokolova, Olesya A., et al.
Publicado: (2019)

Seminal plasma piRNA array analysis and identification of possible biomarker piRNAs for the diagnosis of asthenozoospermia
por: He, Ling, et al.
Publicado: (2022)

piRNN: deep learning algorithm for piRNA prediction
por: Wang, Kai, et al.
Publicado: (2018)

piRBase: a comprehensive database of piRNA sequences
por: Wang, Jiajia, et al.
Publicado: (2019)

piRBase: integrating piRNA annotation in all aspects
por: Wang, Jiajia, et al.
Publicado: (2021)

Small RNA Sequencing Identifies PIWI-Interacting RNAs Deregulated in Glioblastoma—piR-9491 and piR-12488 Reduce Tumor Cell Colonies In Vitro
por: Bartos, Michael, et al.
Publicado: (2021)

piRTarBase: a database of piRNA targeting sites and their roles in gene regulation
por: Wu, Wei-Sheng, et al.
Publicado: (2019)

piRNAs as Modulators of Disease Pathogenesis
por: Rayford, Kayla J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jgl234mk92krbtatav3pni9v92