Antiplatelet Drug Ticagrelor Enhances Chemotherapeutic Efficacy by Targeting the Novel P2Y12-AKT Pathway in Pancreatic Cancer Cells

Background: Extensive research has reported that extracellular ADP in the tumour microenvironment can stimulate platelets through interaction with the platelet receptor P2Y12. In turn, activated platelets release biological factors supporting cancer progression. Experimental data suggest that the tu...

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Detalles Bibliográficos
Autores principales: Elaskalani, Omar, Domenchini, Alice, Abdol Razak, Norbaini Binti, E. Dye, Danielle, Falasca, Marco, Metharom, Pat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016832/
https://www.ncbi.nlm.nih.gov/pubmed/31968611
http://dx.doi.org/10.3390/cancers12010250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016832/
https://www.ncbi.nlm.nih.gov/pubmed/31968611
http://dx.doi.org/10.3390/cancers12010250

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