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TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

Glial cell line-derived neurotrophic factor (GDNF) is expressed at a high level in the human ovary and GDNF signaling is involved in the direct control of follicular activation and oocyte maturation. Transforming growth factor-β1 (TGF-β1) plays an important role in the regulation of various ovarian...

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Detalles Bibliográficos
Autores principales: Yin, Jingwen, Chang, Hsun-Ming, Yi, Yuyin, Yao, Yuanqing, Leung, Peter C.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016865/
https://www.ncbi.nlm.nih.gov/pubmed/31936902
http://dx.doi.org/10.3390/cells9010185