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De-Glycyrrhizinated Licorice Extract Attenuates High Glucose-Stimulated Renal Tubular Epithelial–Mesenchymal Transition via Suppressing the Notch2 Signaling Pathway

Tubulointerstitial fibrosis is a major pathological hallmark of diabetic nephropathy. Increasing evidence has shown that epithelial-to-mesenchymal transition (EMT) of renal proximal tubular cells plays a crucial role in tubulointerstitial fibrosis. Herein, we aimed to elucidate the detailed mechanis...

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Detalles Bibliográficos
Autores principales: Hsu, Yung-Chien, Chang, Pey-Jium, Tung, Chun-Wu, Shih, Ya-Hsueh, Ni, Wen-Chiu, Li, Yi-Chen, Uto, Takuhiro, Shoyama, Yukihiro, Ho, Cheng, Lin, Chun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016866/
https://www.ncbi.nlm.nih.gov/pubmed/31948095
http://dx.doi.org/10.3390/cells9010125