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Angiopoietin1 Deficiency in Hepatocytes Affects the Growth of Colorectal Cancer Liver Metastases (CRCLM)
Colorectal cancer liver metastases (CRCLM) that receive their blood supply via vessel co-option are associated with a poor response to anti-angiogenic therapy. Angiopoietins (Ang1 and Ang2) with their Tyrosine-protein kinase receptor (Tie2) have been shown to support vessel co-option. We demonstrate...
Autores principales: | Ibrahim, Nisreen S., Lazaris, Anthoula, Rada, Miran, Petrillo, Stephanie K., Huck, Laurent, Hussain, Sabah, Ouladan, Shaida, Gao, Zu-Hua, Gregorieff, Alexander, Essalmani, Rachid, Seidah, Nabil G., Metrakos, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016878/ https://www.ncbi.nlm.nih.gov/pubmed/31877668 http://dx.doi.org/10.3390/cancers12010035 |
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