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Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells
Pancreatic ductal adenocarcinoma (PDAC) is amongst the most fatal malignancies and its development is highly associated with inflammatory processes such as chronic pancreatitis (CP). Since the succinate dehydrogenase subunit B (SDHB) is regarded as tumor suppressor that is lost during cancer develop...
Autores principales: | Rahn, Sascha, Dänzer Barbosa, Philippe, Möller, Julia Luisa, Ammar, Nourhane, Demetrowitsch, Tobias, Helm, Ole, Wesch, Daniela, Sipos, Bence, Röcken, Christoph, Schwarz, Karin, Schäfer, Heiner, Sebens, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016879/ https://www.ncbi.nlm.nih.gov/pubmed/31877753 http://dx.doi.org/10.3390/cancers12010042 |
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