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The Expanding Therapeutic Potential of Neuronal KCC2
Dysfunctions in GABAergic inhibitory neural transmission occur in neuronal injuries and neurological disorders. The potassium–chloride cotransporter 2 (KCC2, SLC12A5) is a key modulator of inhibitory GABAergic inputs in healthy adult neurons, as its chloride (Cl(−)) extruding activity underlies the...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016893/ https://www.ncbi.nlm.nih.gov/pubmed/31963584 http://dx.doi.org/10.3390/cells9010240 |