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The Expanding Therapeutic Potential of Neuronal KCC2

Dysfunctions in GABAergic inhibitory neural transmission occur in neuronal injuries and neurological disorders. The potassium–chloride cotransporter 2 (KCC2, SLC12A5) is a key modulator of inhibitory GABAergic inputs in healthy adult neurons, as its chloride (Cl(−)) extruding activity underlies the...

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Detalles Bibliográficos
Autor principal:	Tang, Bor Luen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016893/ https://www.ncbi.nlm.nih.gov/pubmed/31963584 http://dx.doi.org/10.3390/cells9010240

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