Cargando…
Morphology-Controlled Self-Assembly and Synthesis of Biopolyimide Particles from 4-Amino-l-phenylalanine
[Image: see text] Self-assembling polyimides (PIs) having diketopiperazine (DKP) components were synthesized by polycondensation of a 4-amino-l-phenylalanine (4APhe) dimer, an aromatic diamine newly designed in this study. The amino acid-derived PIs showed high thermal resistance, with a 10% weight...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016914/ https://www.ncbi.nlm.nih.gov/pubmed/32064379 http://dx.doi.org/10.1021/acsomega.9b03231 |
_version_ | 1783497085016866816 |
---|---|
author | Hirayama, Thawinda Kumar, Amit Takada, Kenji Kaneko, Tatsuo |
author_facet | Hirayama, Thawinda Kumar, Amit Takada, Kenji Kaneko, Tatsuo |
author_sort | Hirayama, Thawinda |
collection | PubMed |
description | [Image: see text] Self-assembling polyimides (PIs) having diketopiperazine (DKP) components were synthesized by polycondensation of a 4-amino-l-phenylalanine (4APhe) dimer, an aromatic diamine newly designed in this study. The amino acid-derived PIs showed high thermal resistance, with a 10% weight loss temperature (T(d10)) of 432 °C at the maximum, and did not show any glass transition below the thermal decomposition temperature. The poly(amic acid) (PAA) precursors formed nanospheres upon reprecipitation over dimethylacetamide into water. The nanospheres were then added to solvents with different polarities and sonicated to induce deformation of the spherical forms into spiky balls, flakes, or rods. The PAA particle morphologies were retained in the PIs after the two-step imidization. Finally, the PI particles with self-assembling DKP moieties were formed, and their morphologies were fine-tuned using different mixed solvents. |
format | Online Article Text |
id | pubmed-7016914 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Chemical
Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-70169142020-02-14 Morphology-Controlled Self-Assembly and Synthesis of Biopolyimide Particles from 4-Amino-l-phenylalanine Hirayama, Thawinda Kumar, Amit Takada, Kenji Kaneko, Tatsuo ACS Omega [Image: see text] Self-assembling polyimides (PIs) having diketopiperazine (DKP) components were synthesized by polycondensation of a 4-amino-l-phenylalanine (4APhe) dimer, an aromatic diamine newly designed in this study. The amino acid-derived PIs showed high thermal resistance, with a 10% weight loss temperature (T(d10)) of 432 °C at the maximum, and did not show any glass transition below the thermal decomposition temperature. The poly(amic acid) (PAA) precursors formed nanospheres upon reprecipitation over dimethylacetamide into water. The nanospheres were then added to solvents with different polarities and sonicated to induce deformation of the spherical forms into spiky balls, flakes, or rods. The PAA particle morphologies were retained in the PIs after the two-step imidization. Finally, the PI particles with self-assembling DKP moieties were formed, and their morphologies were fine-tuned using different mixed solvents. American Chemical Society 2020-02-03 /pmc/articles/PMC7016914/ /pubmed/32064379 http://dx.doi.org/10.1021/acsomega.9b03231 Text en Copyright © 2020 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes. |
spellingShingle | Hirayama, Thawinda Kumar, Amit Takada, Kenji Kaneko, Tatsuo Morphology-Controlled Self-Assembly and Synthesis of Biopolyimide Particles from 4-Amino-l-phenylalanine |
title | Morphology-Controlled
Self-Assembly and Synthesis
of Biopolyimide Particles from 4-Amino-l-phenylalanine |
title_full | Morphology-Controlled
Self-Assembly and Synthesis
of Biopolyimide Particles from 4-Amino-l-phenylalanine |
title_fullStr | Morphology-Controlled
Self-Assembly and Synthesis
of Biopolyimide Particles from 4-Amino-l-phenylalanine |
title_full_unstemmed | Morphology-Controlled
Self-Assembly and Synthesis
of Biopolyimide Particles from 4-Amino-l-phenylalanine |
title_short | Morphology-Controlled
Self-Assembly and Synthesis
of Biopolyimide Particles from 4-Amino-l-phenylalanine |
title_sort | morphology-controlled
self-assembly and synthesis
of biopolyimide particles from 4-amino-l-phenylalanine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016914/ https://www.ncbi.nlm.nih.gov/pubmed/32064379 http://dx.doi.org/10.1021/acsomega.9b03231 |
work_keys_str_mv | AT hirayamathawinda morphologycontrolledselfassemblyandsynthesisofbiopolyimideparticlesfrom4aminolphenylalanine AT kumaramit morphologycontrolledselfassemblyandsynthesisofbiopolyimideparticlesfrom4aminolphenylalanine AT takadakenji morphologycontrolledselfassemblyandsynthesisofbiopolyimideparticlesfrom4aminolphenylalanine AT kanekotatsuo morphologycontrolledselfassemblyandsynthesisofbiopolyimideparticlesfrom4aminolphenylalanine |