Tissue-Specificity of Dystrophin–Actin Interactions: Isoform-Specific Thermodynamic Stability and Actin-Binding Function of Tandem Calponin-Homology Domains

[Image: see text] Genetic mutations in Duchenne muscular dystrophy (DMD) gene affecting the expression of dystrophin protein lead to a number of muscle disorders collectively called dystrophinopathies. In addition to muscle dystrophin, mutations in brain-specific dystrophin isoforms, in particular t...

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Detalles Bibliográficos
Autores principales: Upadhyay, Vaibhav, Bandi, Swati, Panja, Sudipta, Saba, Laura, Mallela, Krishna M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016916/
https://www.ncbi.nlm.nih.gov/pubmed/32064376
http://dx.doi.org/10.1021/acsomega.9b02911

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