Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells

Glioblastoma (GBM) stem cells (GSCs), which contribute to GBM unfavorable prognosis, show high expression levels of ATP/P2X7 receptors (P2X7R). Here, we reported that cells exposure to 2’(3’)-O-(4-benzoylbenzoyl)-ATP (BzATP), a P2X7R agonist, up-regulated the expression of markers associated to epit...

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Detalles Bibliográficos
Autores principales: Ziberi, Sihana, Zuccarini, Mariachiara, Carluccio, Marzia, Giuliani, Patricia, Ricci-Vitiani, Lucia, Pallini, Roberto, Caciagli, Francesco, Di Iorio, Patrizia, Ciccarelli, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016938/
https://www.ncbi.nlm.nih.gov/pubmed/31905754
http://dx.doi.org/10.3390/cells9010085

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