Cargando…

Plasma Membrane Ca(2+) ATPase Isoform 4 (PMCA4) Has an Important Role in Numerous Hallmarks of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is largely resistant to standard treatments leading to poor patient survival. The expression of plasma membrane calcium ATPase-4 (PMCA4) is reported to modulate key cancer hallmarks including cell migration, growth, and apoptotic resistance. Data-mining reveal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sritangos, Pishyaporn, Pena Alarcon, Eduardo, James, Andrew D., Sultan, Ahlam, Richardson, Daniel A., Bruce, Jason I. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016988/ https://www.ncbi.nlm.nih.gov/pubmed/31963119 http://dx.doi.org/10.3390/cancers12010218

Ejemplares similares

Plasma Membrane Ca(2+) Pump PMCA4z Is More Active Than Splicing Variant PMCA4x
por: Corradi, Gerardo R., et al.
Publicado: (2021)

Ca(2+) Homeostasis by Plasma Membrane Ca(2+) ATPase (PMCA) 1 Is Essential for the Development of DP Thymocytes
por: Beckmann, David, et al.
Publicado: (2023)

Expression and Secretion of Plasma Membrane Ca(2+)-ATPase 4a (PMCA4a) during Murine Estrus: Association with Oviductal Exosomes and Uptake in Sperm
por: Al-Dossary, Amal A., et al.
Publicado: (2013)

Crosstalk among Calcium ATPases: PMCA, SERCA and SPCA in Mental Diseases
por: Boczek, Tomasz, et al.
Publicado: (2021)

The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process
por: Boczek, Tomasz, et al.
Publicado: (2019)

Plasma membrane calcium ATPase (PMCA4): A housekeeper for RT-PCR relative quantification of polytopic membrane proteins
por: Calcagno, Anna Maria, et al.
Publicado: (2006)

The plasma membrane calcium ATPase (PMCA) of neurones is electroneutral and exchanges 2 H(+) for each Ca(2+) or Ba(2+) ion extruded
por: Thomas, Roger C
Publicado: (2009)

The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin
por: Peters, Amelia A., et al.
Publicado: (2016)

Chrysophyllum cainito stem bark extract induces apoptosis in Human hepatocarcinoma HepG2 cells through ROS-mediated mitochondrial pathway
por: Doan, Hau V., et al.
Publicado: (2020)

NFAT1 and NFAT3 Cooperate with HDAC4 during Regulation of Alternative Splicing of PMCA Isoforms in PC12 Cells
por: Kosiorek, Michalina, et al.
Publicado: (2014)

The Plasma Membrane Ca(2+)-ATPase2 (PMCA2) Is Involved in the Regulation of Purkinje Cell Dendritic Growth in Cerebellar Organotypic Slice Cultures
por: Sherkhane, Pradeep, et al.
Publicado: (2013)

PMCA4 (ATP2B4) Mutation in Familial Spastic Paraplegia
por: Li, Miaoxin, et al.
Publicado: (2014)

Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2)
por: James, Andrew D., et al.
Publicado: (2019)

The Plasma Membrane Ca(2+) Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton
por: Naffa, Randa, et al.
Publicado: (2021)

Metabolic regulation of the PMCA: Role in cell death and survival()
por: Bruce, Jason I.E.
Publicado: (2018)

Treatment with specific and pan-plasma membrane calcium ATPase (PMCA) inhibitors reduces malaria parasite growth in vitro and in vivo
por: Asih, Puji B. S., et al.
Publicado: (2022)

The Whitish Inner Mantle of the Giant Clam, Tridacna squamosa, Expresses an Apical Plasma Membrane Ca(2+)-ATPase (PMCA) Which Displays Light-Dependent Gene and Protein Expressions
por: Ip, Yuen K., et al.
Publicado: (2017)

Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?
por: van Loon, Ellen P. M., et al.
Publicado: (2016)

PMCA4 gene expression is regulated by the androgen receptor in the mouse testis during spermatogenesis
por: Sun, Rui, et al.
Publicado: (2021)

Renalase and its receptor, PMCA4b, are expressed in the placenta throughout the human gestation
por: Wang, Melinda, et al.
Publicado: (2022)

Differential expression of PMCA2 mRNA isoforms in a cohort of Spanish patients with breast tumor types
por: Romero-Lorca, Alicia, et al.
Publicado: (2018)

The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition
por: Hegedüs, Luca, et al.
Publicado: (2022)

Hallmarks of Hunds coupling in the Mott insulator Ca(2)RuO(4)
por: Sutter, D., et al.
Publicado: (2017)

PMCA4 (ATP2B4) mutation in familial spastic paraplegia causes delay in intracellular calcium extrusion
por: Ho, Philip Wing-Lok, et al.
Publicado: (2015)

A link between plasma membrane calcium ATPase 2 (PMCA2), estrogen and estrogen receptor α signaling in mechanical pain
por: Khariv, Veronika, et al.
Publicado: (2018)

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK
por: Hegedüs, Luca, et al.
Publicado: (2017)

Pathological pain processing in mouse models of multiple sclerosis and spinal cord injury: contribution of plasma membrane calcium ATPase 2 (PMCA2)
por: Mirabelli, Ersilia, et al.
Publicado: (2019)

Ontogeny of ATP hydrolysis and isoform expression of the Plasma Membrane Ca(2+)-ATPase in mouse brain
por: Marcos, Daniel, et al.
Publicado: (2009)

PMCA for ultrasensitive detection of prions and to study disease biology
por: Wang, Fei, et al.
Publicado: (2022)

Separation of presynaptic Ca(v)2 and Ca(v)1 channel function in synaptic vesicle exo- and endocytosis by the membrane anchored Ca(2+) pump PMCA
por: Krick, Niklas, et al.
Publicado: (2021)

Effect of Mg-Gluconate on the Osmotic Fragility of Red Blood Cells, Lipid Peroxidation, and Ca(2+)-ATPase (PMCA) Activity of Placental Homogenates and Red Blood Cell Ghosts From Salt-Loaded Pregnant Rats
por: Rojas, Deliana, et al.
Publicado: (2022)

Acute oral toxicity evaluation of Andrographis paniculata-standardized first true leaf ethanolic extract
por: Worasuttayangkurn, Luksamee, et al.
Publicado: (2019)

Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast
por: Banerjee, Subhrajit, et al.
Publicado: (2017)

Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants
por: Mózner, Orsolya, et al.
Publicado: (2021)

PMCA4 inhibition does not affect cardiac remodelling following myocardial infarction, but may reduce susceptibility to arrhythmia
por: Stafford, Nicholas, et al.
Publicado: (2021)

Regulation of GAP43/calmodulin complex formation via calcineurin-dependent mechanism in differentiated PC12 cells with altered PMCA isoforms composition
por: Boczek, Tomasz, et al.
Publicado: (2015)

A Selective PMCA Inhibitor Does Not Prolong the Electroolfactogram in Mouse
por: Griff, Edwin R., et al.
Publicado: (2012)

Neuroplastin expression is essential for hearing and hair cell PMCA expression
por: Lin, Xiao, et al.
Publicado: (2021)

Metabolic regulation of calcium pumps in pancreatic cancer: role of phosphofructokinase-fructose-bisphosphatase-3 (PFKFB3)
por: Richardson, D. A., et al.
Publicado: (2020)

P38 MAPK Promotes Migration and Metastatic Activity of BRAF Mutant Melanoma Cells by Inducing Degradation of PMCA4b
por: Naffa, Randa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9aret0969k85g99ueg2bd8htun