Cargando…
Activation of STAT3 and STAT5 Signaling in Epithelial Ovarian Cancer Progression: Mechanism and Therapeutic Opportunity
Epithelial ovarian cancer (EOC) is the most lethal of all gynecologic malignancies. Despite advances in surgical and chemotherapeutic options, most patients with advanced EOC have a relapse within three years of diagnosis. Unfortunately, recurrent disease is generally not curable. Recent advances in...
Autores principales: | Wu, Chin-Jui, Sundararajan, Vignesh, Sheu, Bor-Ching, Huang, Ruby Yun-Ju, Wei, Lin-Hung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017004/ https://www.ncbi.nlm.nih.gov/pubmed/31861720 http://dx.doi.org/10.3390/cancers12010024 |
Ejemplares similares
-
STAT3 signaling in ovarian cancer: a potential therapeutic target
por: Liang, Renba, et al.
Publicado: (2020) -
JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies
por: Rah, Bilal, et al.
Publicado: (2022) -
Spotlight on the Granules (Grainyhead-Like Proteins) – From an Evolutionary Conserved Controller of Epithelial Trait to Pioneering the Chromatin Landscape
por: Sundararajan, Vignesh, et al.
Publicado: (2020) -
Sonographic features differentiating early-stage ovarian clear cell carcinoma from endometrioma with atypical features
por: Huang, Kuan-Ju, et al.
Publicado: (2022) -
Type I IFN induced IL1-Ra expression in hepatocytes is mediated by activating STAT6 through the formation of STAT2: STAT6 heterodimer
por: Wan, Lei, et al.
Publicado: (2008)