Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways

Disulfiram/copper (DSF/Cu) is a promising antitumor reagent for clinical application due to its excellent anticancer activity and safety. However, the anticancer mechanism of DSF/Cu has not been fully elucidated. Our study showed that DSF/Cu strongly induced cytotoxic effects on both nasopharyngeal...

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Detalles Bibliográficos
Autores principales: Li, Yiqiu, Chen, Fangfang, Chen, Jun, Chan, Siocheong, He, Yi, Liu, Wanli, Zhang, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017005/
https://www.ncbi.nlm.nih.gov/pubmed/31935835
http://dx.doi.org/10.3390/cancers12010138

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