Cargando…

Synergistic Effects of N-Acetylcysteine and Mesenchymal Stem Cell in a Lipopolysaccharide-Induced Interstitial Cystitis Rat Model

The purpose of this study was to reduce the amount of stem cells used in treating preclinical interstitial cystitis (IC model) by investigating the synergistic effects of multipotent mesenchymal stem cells (M-MSCs; human embryonic stem cell-derived) and N-acetylcysteine (NAC). Eight-week-old female...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Jung Hyun, Ryu, Chae-Min, Ju, Hyein, Yu, Hwan Yeul, Song, Sujin, Shin, Dong-Myung, Choo, Myung-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017055/ https://www.ncbi.nlm.nih.gov/pubmed/31905757 http://dx.doi.org/10.3390/cells9010086

Ejemplares similares

N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model
por: Ryu, Chae-Min, et al.
Publicado: (2019)

Therapeutic effects of axitinib, an anti-angiogenic tyrosine kinase inhibitor, on interstitial cystitis
por: Shin, Jung Hyun, et al.
Publicado: (2023)

Longitudinal intravital imaging of transplanted mesenchymal stem cells elucidates their functional integration and therapeutic potency in an animal model of interstitial cystitis/bladder pain syndrome
por: Ryu, Chae-Min, et al.
Publicado: (2018)

Safety of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells for Treating Interstitial Cystitis: A Phase I Study
por: Shin, Jung Hyun, et al.
Publicado: (2022)

Downregulation of WNT11 is associated with bladder tissue fibrosis in patients with interstitial cystitis/bladder pain syndrome without Hunner lesion
por: Choi, Daeheon, et al.
Publicado: (2018)

The Therapeutic Effect of Human Embryonic Stem Cell-Derived Multipotent Mesenchymal Stem Cells on Chemical-Induced Cystitis in Rats
por: Lee, Sang Wook, et al.
Publicado: (2018)

Therapeutic Efficacy of Human Embryonic Stem Cell-Derived Multipotent Stem/Stromal Cells in Diabetic Detrusor Underactivity: A Preclinical Study
por: Shin, Jung Hyun, et al.
Publicado: (2020)

Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder
por: Kim, Aram, et al.
Publicado: (2016)

Evaluation of the incidence and risk factors associated with persistent frequency in interstitial cystitis/bladder pain syndrome and the efficacy of antimuscarinic treatment
por: Kim, Aram, et al.
Publicado: (2017)

Current and Future Directions of Stem Cell Therapy for Bladder Dysfunction
por: Shin, Jung Hyun, et al.
Publicado: (2019)

Elimination of Hunner's Ulcers by Fulguration in Patients With Interstitial Cystitis: Is It Effective and Long Lasting?
por: Ryu, Jeman, et al.
Publicado: (2013)

Induction of detrusor underactivity by extensive vascular endothelial damages of iliac arteries in a rat model and its pathophysiology in the genetic levels
por: Kim, Myong, et al.
Publicado: (2019)

Small‐sized mesenchymal stem cells with high glutathione dynamics show improved therapeutic potency in graft‐versus‐host disease
por: Lim, Jisun, et al.
Publicado: (2021)

Pretreatment Features to Influence Effectiveness of Intravesical Hyaluronic Acid Instillation in Refractory Interstitial Cystitis/Painful Bladder Syndrome
por: Kim, Aram, et al.
Publicado: (2014)

A Preclinical Study of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells for Treating Detrusor Underactivity by Chronic Bladder Ischemia
por: Yu, Hwan Yeul, et al.
Publicado: (2021)

N-acetylcysteine modulates lipopolysaccharide-induced intestinal dysfunction
por: Lee, Sang In, et al.
Publicado: (2019)

Small hypoxia-primed mesenchymal stem cells attenuate graft-versus-host disease
por: Kim, YongHwan, et al.
Publicado: (2018)

Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway
por: Lim, Jisun, et al.
Publicado: (2020)

Clinical Remission Using Personalized Low-Dose Intravenous Infusions of N-acetylcysteine with Minimal Toxicities for Interstitial Cystitis/Bladder Pain Syndrome
por: Maharaj, Dipnarine, et al.
Publicado: (2021)

Interleukin-33 as a Potential Therapeutic Target for Interstitial Cystitis: New Perspectives on Mast Cell Regulation
por: Choo, Min Soo
Publicado: (2015)

Verification of mesenchymal stem cell injection therapy for interstitial cystitis in a rat model
por: Chung, Jae-Wook, et al.
Publicado: (2019)

Co-Morbidities of Interstitial Cystitis
por: Chelimsky, Gisela, et al.
Publicado: (2012)

Interstitial cystitis intravesical therapy
por: Ha, Tanya, et al.
Publicado: (2017)

Potential Targeting of Siglecs, Mast Cell Inhibitory Receptors, in Interstitial Cystitis
por: Park, Chang-Shin, et al.
Publicado: (2011)

Development of the Interstitial Cystitis Self-Help and Medical Resources Scale (ICSR) for Women with Interstitial Cystitis
por: Chen, Hui-Chun, et al.
Publicado: (2022)

Roles of mesenchymal stem cells and exosomes in interstitial cystitis/bladder pain syndrome
por: Wen, Chao, et al.
Publicado: (2021)

Current guidelines in the management of interstitial cystitis
por: Colaco, Marc, et al.
Publicado: (2015)

How does interstitial cystitis begin?
por: Parsons, C. Lowell
Publicado: (2015)

An update on treatment options for interstitial cystitis
por: Garzon, Simone, et al.
Publicado: (2020)

Therapeutic effect of urine-derived stem cells for protamine/lipopolysaccharide-induced interstitial cystitis in a rat model
por: Li, Jia, et al.
Publicado: (2017)

Non-Hunner's Interstitial Cystitis Is Different from Hunner's Interstitial Cystitis and May Be Curable by Uterosacral Ligament Repair
por: Goeschen, Klaus, et al.
Publicado: (2022)

The Use of Urine Proteomic and Metabonomic Patterns for the Diagnosis of Interstitial Cystitis and Bacterial Cystitis
por: Van, Que N., et al.
Publicado: (2004)

Urinary extracellular vesicle microRNA profiling for detection in patients with interstitial cystitis
por: Urabe, Fumihiko, et al.
Publicado: (2022)

Activating transcription factor-2 supports the antioxidant capacity and ability of human mesenchymal stem cells to prevent asthmatic airway inflammation
por: Ju, Hyein, et al.
Publicado: (2023)

The Effect of Acetylcysteine on Renal Function in Experimental Models of Cyclophosphamide-and Ifosfamide-Induced Cystitis: Erratum
Publicado: (2021)

From interstitial cystitis to chronic pelvic pain
por: Persu, C, et al.
Publicado: (2010)

Metabolomics Insights Into Pathophysiological Mechanisms of Interstitial Cystitis
por: Fiehn, Oliver, et al.
Publicado: (2014)

Recent advances in imaging and understanding interstitial cystitis
por: Tyagi, Pradeep, et al.
Publicado: (2018)

Interstitial cystitis: an enigmatic disorder of unclear aetiology
por: Moutzouris, Dimitrios-Anestis, et al.
Publicado: (2008)

Monoclonal Antibody Therapy for the Treatment of Interstitial Cystitis
por: Mykoniatis, Ioannis, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ba86plstdcun8ifpvddqqfih89