Galectin-8 binds to the Farnesylated C-terminus of K-Ras4B and Modifies Ras/ERK Signaling and Migration in Pancreatic and Lung Carcinoma Cells

K-Ras is the most prominent driver of oncogenesis and no effective K-Ras inhibitors have been established despite decades of intensive research. Identifying new K-Ras-binding proteins and their interaction domains offers the opportunity for defining new approaches in tackling oncogenic K-Ras. We hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Meinohl, Christopher, Barnard, Sarah J., Fritz-Wolf, Karin, Unger, Monika, Porr, Andreea, Heipel, Marisa, Wirth, Stefanie, Madlung, Johannes, Nordheim, Alfred, Menke, Andre, Becker, Katja, Giehl, Klaudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017085/
https://www.ncbi.nlm.nih.gov/pubmed/31861875
http://dx.doi.org/10.3390/cancers12010030

Ejemplares similares

Ejemplares similares