PIK3CA Gene Mutations in Solid Malignancies: Association with Clinicopathological Parameters and Prognosis

Phosphoinositide kinases (PIKs) are a group of lipid kinases that are important upstream activators of various significant signaling pathways. Hyperactivation of the PI3K/AKT/mTOR pathways—either via mutations or genomic amplification—confers key oncogenic activity, essential for the development and...

Descripción completa

Detalles Bibliográficos
Autores principales: Alqahtani, Ali, Ayesh, Hazem S. K., Halawani, Hafez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017171/
https://www.ncbi.nlm.nih.gov/pubmed/31905960
http://dx.doi.org/10.3390/cancers12010093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017171/
https://www.ncbi.nlm.nih.gov/pubmed/31905960
http://dx.doi.org/10.3390/cancers12010093

Ejemplares similares