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Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death
It is believed that mitochondrial fragmentation cause mitochondrial dysfunction and neuronal deficits in Alzheimer’s disease. We recently reported that constitutive knockout of the mitochondria fusion protein mitofusin2 (Mfn2) in the mouse brain causes mitochondrial fragmentation and neurodegenerati...
Autores principales: | Han, Song, Nandy, Priya, Austria, Quillan, Siedlak, Sandra L., Torres, Sandy, Fujioka, Hisashi, Wang, Wenzhang, Zhu, Xiongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017224/ https://www.ncbi.nlm.nih.gov/pubmed/31947766 http://dx.doi.org/10.3390/cells9010116 |
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