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The Diverse Roles of TIMP-3: Insights into Degenerative Diseases of the Senescent Retina and Brain
Tissue inhibitor of metalloproteinase-3 (TIMP-3) is a component of the extracellular environment, where it mediates diverse processes including matrix regulation/turnover, inflammation and angiogenesis. Rare TIMP-3 risk alleles and mutations are directly linked with retinopathies such as age-related...
Autores principales: | Dewing, Jennifer M., Carare, Roxana O., Lotery, Andrew J., Ratnayaka, J. Arjuna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017234/ https://www.ncbi.nlm.nih.gov/pubmed/31877820 http://dx.doi.org/10.3390/cells9010039 |
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